Bayes Factor Reference

How to use this document: Each test has a Bayes factor — a round number you can do in your head. After a positive result, multiply the prior by the Bayes factor. After a negative result, divide. When a test is much stronger in one direction, separate positive and negative Bayes factors are reported.

Pr[Disease | Positive test] ≈ BF × Prior

All Bayes factors are rounded to mental-math-friendly values: 1.5, 2, 3, 5, 10, 20, 50, or 100.

Because BF × Prior is a shortcut, the result can exceed 100%. Don't worry about it. Approach is still informative. When BF × Prior ≈ 100%, interpret it as "more likely than not to have the disease." When BF × Prior > 200%, interpret it as "very likely to have the disease." In these cases, the exact calculation is given below the table.

Probability anchors — what these numbers feel like:

Probability Feels like...
0.01% (1 in 10,000) Being in a fatal car crash this year
0.1% (1 in 1,000) Developing appendicitis this year
0.5% (1 in 200) Being an identical twin
1% (1 in 100) Having a shellfish allergy
2% (1 in 50) Having naturally red hair
5% (1 in 20) Being a vegetarian
10% (1 in 10) Being left-handed
20% (1 in 5) Drawing a face card from a shuffled deck
50% (1 in 2) A coin flip

Sources: NHTSA 2024 (39,345 US traffic fatalities / 335M population); StatPearls appendicitis (1.1 per 1,000/year); CDC twin birth data (3–4 per 1,000 births monozygotic); FARE shellfish allergy (~1.3%); global red hair prevalence (~2%); Gallup US vegetarian poll (~5%); handedness meta-analyses (~10%); card probability (12 face cards / 52 = 23%, ≈ 20%); coin symmetry.


Breast CancerCancer Screening

Mammography (Digital)

BF+: 10×BF−: 1/10×Base: 1% of women undergoing screening
Prostate CancerCancer Screening

PSA

BF+: 1.5×BF−: 1/3×Base: 5% of men aged 55–69
Lung CancerCancer Screening

Low-Dose CT (LDCT)

BF+: 20×BF−: 1/20×Base: 2% in high-risk smokers
Colorectal CancerCancer Screening

Colonoscopy

BF+: 100×Base: 0.5% average-risk adults
Colorectal CancerCancer Screening

FIT (Fecal Immunochemical Test)

BF+: 10×BF−: 1/5×Base: 0.5% average-risk adults
Colorectal CancerCancer Screening

Cologuard (Multi-target Stool DNA)

BF+: 5×BF−: 1/10×Base: 0.5% average-risk adults
Cervical CancerCancer Screening

Pap Smear

BF+: 20×BF−: 1/2×Base: 0.1% screened women
Acute Myocardial InfarctionCardiac

High-Sensitivity Troponin

BF+: 3×BF−: 1/10×Base: 10% ED chest pain
Heart FailureCardiac

NT-proBNP

BF+: 5×BF−: 1/10×Base: 2% primary care adults
Pulmonary EmbolismCardiac

D-dimer

BF+: 1.5×BF−: 1/10×Base: 5% suspected PE
Type 2 DiabetesMetabolic & Endocrine

Hemoglobin A1c (≥6.5%)

BF+: 10×BF−: 1/2×Base: 5% US adults
Type 2 DiabetesMetabolic & Endocrine

Fasting Plasma Glucose (≥126 mg/dL)

BF+: 50×BF−: 1/2×Base: 5% US adults
HypothyroidismMetabolic & Endocrine

TSH

BF+: 10×BF−: 1/50×Base: 5% US adults
Group A Streptococcal PharyngitisInfectious Disease

Rapid Strep Test (RADT)

BF+: 20×BF−: 1/5×Base: 15% adults; 30% children
InfluenzaInfectious Disease

Rapid Influenza Diagnostic Test (RIDT)

BF+: 50×BF−: 1/3×Base: 15% during flu season
COVID-19Infectious Disease

COVID-19 Rapid Antigen Test

BF+: 100×BF−: 1/3×Base: 5–20% depending on transmission
Infectious Mononucleosis (EBV)Infectious Disease

Monospot

BF+: 20×BF−: 1/5×Base: 5% adolescents/young adults
H. pylori InfectionInfectious Disease

Urea Breath Test

BF+: 10×BF−: 1/10×Base: 30% US adults
HIVInfectious Disease

Rapid Antibody Test

BF+: 100×BF−: 1/100×Base: 0.5% US adults
Hepatitis CInfectious Disease

Antibody Screen

BF+: 100×BF−: 1/50×Base: 2% US adults
SyphilisInfectious Disease

RPR/VDRL

BF+: 20×BF−: 1/5×Base: 0.1% general population
Chlamydia/GonorrheaInfectious Disease

NAAT

BF+: 50×BF−: 1/20×Base: 5% sexually active women <25
Latent TuberculosisInfectious Disease

QuantiFERON-TB Gold

BF+: 20×BF−: 1/20×Base: 5% US population
Urinary Tract InfectionUrinary

Urine Nitrite

BF+: 10×BF−: 1/1.5×Base: 50% symptomatic women
Urinary Tract InfectionUrinary

Urine Leukocyte Esterase

BF+: 3×BF−: 1/3×Base: 50% symptomatic women
Iron Deficiency AnemiaHematologic

Ferritin (<30 ng/mL)

BF+: 50×BF−: 1/10×Base: 5% adult women; 2% men
Systemic Lupus ErythematosusRheumatologic & Autoimmune

ANA (1:80 titer)

BF+: 5×BF−: 1/50×Base: 0.1% general adult population
Systemic Lupus ErythematosusRheumatologic & Autoimmune

ANA (≥1:320 titer)

BF+: 20×BF−: 1/50×Base: 0.1% general adult population
Rheumatoid ArthritisRheumatologic & Autoimmune

Anti-CCP

BF+: 10×BF−: 1/3×Base: 0.5% US adults
Rheumatoid ArthritisRheumatologic & Autoimmune

Rheumatoid Factor (RF)

BF+: 5×BF−: 1/5×Base: 0.5% US adults
Celiac DiseaseGastrointestinal

tTG-IgA

BF+: 10×BF−: 1/20×Base: 1% general population
Community-Acquired PneumoniaRespiratory

Chest X-Ray

BF+: 5×BF−: 1/5×Base: 5% cough and fever
COPDRespiratory

Spirometry (FEV1/FVC < 0.70)

BF+: 5×BF−: 1/10×Base: 5% US adults